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Product Name Semaphorin 3B Chinese Name 导向蛋白3B抗体 Alias Semaphorin3B; Semaphorin-3B; Semaphorin 3 B; Sema A(V); Sema V; Semaphorin V; SEMA3B; LUCA-1; SemA; SEMA5; SEMAA; semaV; semaphorin-3B isoform 2; SEM3B_HUMAN; Semaphorin-V; Sema V.. Research Area Tumour immunology Developmental biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 82kDa Cellular localization cytoplasmic Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Semaphorin 3B.: 701-749/749 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis. [provided by RefSeq, Jul2008].
Function:
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Subcellular Location:
Secreted. Endoplasmic reticulum. Note=Accumulates in the endoplasmic reticulum.
Tissue Specificity:
Expressed abundantly but differentially in a variety of neural and nonneural tissues.
Similarity:
Belongs to the semaphorin family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 PSI domain.
Contains 1 Sema domain.
SWISS:
Q13214
Gene ID:
7869
Database links:Entrez Gene: 7869 Human
Entrez Gene: 20347 Mouse
Omim: 601281 Human
SwissProt: Q13214 Human
SwissProt: Q0VGP2 Mouse
SwissProt: Q62177 Mouse
Unigene: 82222 Human
Unigene: 4083 Mouse
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