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Product Name FGF17 Chinese Name 成纤维细胞生长因子17抗体 Alias FGF17; FGF-17; FGF 17; Fibroblast growth factor 17; FGF17_HUMAN. Research Area Tumour Cardiovascular immunology Signal transduction Growth factors and hormones Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 22kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FGF17: 81-180/216 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FGF17 belongs to the heparin-binding growth factors family. It may be a signaling molecule in the induction and patterning of the embryonic brain and is preferentially expressed in the embryonic brain. There are two named isoforms.
Function:
Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.
Subunit:
Interacts with FGFR3 and FGFR4.
Subcellular Location:
Secreted.
Tissue Specificity:
Preferentially expressed in the embryonic brain.
Similarity:
Belongs to the heparin-binding growth factors family.
SWISS:
O60258
Gene ID:
8822
Database links:Entrez Gene: 8822 Human
Omim: 603725 Human
SwissProt: O60258 Human
Unigene: 248192 Human
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