Product Name	CIAPIN1
Chinese Name	cell factor诱导凋亡抑制因子1
Alias	Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.
Research Area	Tumour  Cell biology  immunology  Apoptosis
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Pig, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CIAPIN1: 51-150/312
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1. Function: May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitously expressed. Highly expressed in heart, liver and pancreas. Similarity: Belongs to the anamorsin family. SWISS: Q6FI81 Gene ID: 57019 Database links: Entrez Gene: 57019 Human Entrez Gene: 109006 Mouse Omim: 608943 Human SwissProt: Q6FI81 Human SwissProt: Q8WTY4 Mouse Unigene: 4900 Human Unigene: 27582 Mouse
Product Picture	Sample: Heart (mouse) Cell Lysate at 40 ug Primary: Anti- CIAPIN1(SL5764R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34kD Observed band size: 36 kD Sample: Hcclm3 (human)cell Lysate at 40 ug Primary: Anti- CIAPIN1(SL5764R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34kD Observed band size: 36 kD

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