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Rabbit Anti-MPP6 antibody
Rabbit Anti-MPP6 antibody
MAGUK p55 subfamily member 6 VELI associated MAGUK 1; MAGUK protein p55T; MPP6; Palmitoylated 6 MAGUK p55 subfamily member 6; PALS2; Protein associated with Lin7 2; VELI associated MAGUK 1; MPP6_HUMAN.
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  • NO.:SL5756R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name MPP6
Chinese Name 棕榈酰化膜蛋白6抗体
Alias MAGUK p55 subfamily member 6 VELI associated MAGUK 1; MAGUK protein p55T; MPP6; Palmitoylated 6 MAGUK p55 subfamily member 6; PALS2; Protein associated with Lin7 2; VELI associated MAGUK 1; MPP6_HUMAN.  
Research Area Tumour  Cell biology  immunology  Chromatin and nuclear signals  Cyclin  Kinases and Phosphatases  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 61kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human VAM1/MPP6: 431-540/540 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase promoting factor, or MPF. In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M phase phosphoproteins (MPPs, or MPHOSPHs) permit disassembly of interphase structures and generation of M phase enzymatic activities and structures. VAM1 or MPP6 is thought to be a nucleolus specific exosome co factor, required for its role in the maturation of 5.8S rRNA.

Subunit:
Interacts with CADM1 (By similarity). Interacts with the LIN7 proteins.

Subcellular Location:
Membrane; Peripheral membrane protein (By similarity).

Tissue Specificity:
Abundant in testis, brain, and kidney with lower levels detectable in other tissues.

Similarity:
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 2 L27 domains.
Contains 1 PDZ (DHR) domain.
Contains 1 SH3 domain.

SWISS:
Q9NZW5

Gene ID:
51678

Database links:

Entrez Gene: 51678 Human

Entrez Gene: 56524 Mouse

Entrez Gene: 362359 Rat

Omim: 606959 Human

SwissProt: Q9NZW5 Human

SwissProt: Q9JLB0 Mouse

Unigene: 533355 Human



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