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Product Name CKS1 Chinese Name Cyclin依赖性激酶调节亚基1抗体 Alias CDC2 associated protein CKS1; CDC28 protein kinase 1; CDC28 protein kinase 1B; CDC28 protein kinase regulatory subunit 1B; Cell division control protein CKS1; CKS 1; CKS1B; Ckshs1; Cyclin dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS 143; PNAS 16; PNAS 18. Research Area Tumour Cell biology immunology Cyclin Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 9.6kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CKS1: 21-79/79 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CKS1 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.
Function:
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
Subunit:
Forms a homohexamer that can probably bind six kinase subunits.
Similarity:
Belongs to the CKS family.
SWISS:
P61024
Gene ID:
1163
Database links:Entrez Gene: 1163 Human
Entrez Gene: 54124 Mouse
Omim: 116900 Human
SwissProt: P61024 Human
SwissProt: P61025 Mouse
Unigene: 374378 Human
Unigene: 3049 Mouse
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