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Rabbit Anti-TNFSF13 antibody
Rabbit Anti-TNFSF13 antibody
APRIL; Tumor necrosis factor ligand superfamily member 13; Tumor necrosis factor (ligand) superfamily member 13; Tumor necrosis factor related death ligand; Tumor necrosis factor related death ligand 1; A proliferation inducing ligand; A proliferation-ind
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  • NO.:SL5725R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,)
    Applications:ELISA IHC-P IHC-F Flow-Cyt IF
    concentration:1mg/ml
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Details

Product Name TNFSF13
Chinese Name Tumour坏死因子配体超家族成员13抗体
Alias APRIL; Tumor necrosis factor ligand superfamily member 13; Tumor necrosis factor (ligand) superfamily member 13; Tumor necrosis factor related death ligand; Tumor necrosis factor related death ligand 1; A proliferation inducing ligand; A proliferation-inducing ligand; APRIL; CD 256; CD256; CD256 antigen; Proliferation inducing ligand APRIL; TALL 2; TALL-2; TALL2; TNF and APOL related leukocyte expressed ligand 2; TNF related death ligand 1; TNF related death ligand; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; TNFSF 13; TRDL 1; TRDL-1; TRDL1; TWE PRIL; ZTNF2; TNF13_HUMAN.  
Research Area Tumour  immunology  Cyclin  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=3μg/Test IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 16kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human TNFSF13/APRIL: 21-120/250 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.

Function:
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.

Subunit:
Homotrimer (Potential).

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.

Post-translational modifications:
The precursor is cleaved by furin.

Similarity:
Belongs to the tumor necrosis factor family.

SWISS:
O75888

Gene ID:
8741

Database links:

Entrez Gene: 8741 Human

Entrez Gene: 69583 Mouse

Entrez Gene: 287437 Rat

Omim: 604472 Human

SwissProt: O75888 Human

SwissProt: Q9D777 Mouse

Unigene: 54673 Human

Unigene: 8983 Mouse

Unigene: 19955 Rat



Product Picture
Blank control(blue): Jurkat cells(fixed with 2% paraformaldehyde (10 min)).
Primary Antibody:Rabbit Anti-APRIL/TNFSF13 antibody(SL5725R), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions );
Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

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