TEL: +86 571 56623320 EMAIL: [email protected]
Product Name TNFSF13 Chinese Name Tumour坏死因子配体超家族成员13抗体 Alias APRIL; Tumor necrosis factor ligand superfamily member 13; Tumor necrosis factor (ligand) superfamily member 13; Tumor necrosis factor related death ligand; Tumor necrosis factor related death ligand 1; A proliferation inducing ligand; A proliferation-inducing ligand; APRIL; CD 256; CD256; CD256 antigen; Proliferation inducing ligand APRIL; TALL 2; TALL-2; TALL2; TNF and APOL related leukocyte expressed ligand 2; TNF related death ligand 1; TNF related death ligand; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; TNFSF 13; TRDL 1; TRDL-1; TRDL1; TWE PRIL; ZTNF2; TNF13_HUMAN. Research Area Tumour immunology Cyclin The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=3μg/Test IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 16kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TNFSF13/APRIL: 21-120/250 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Function:
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Subunit:
Homotrimer (Potential).
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Post-translational modifications:
The precursor is cleaved by furin.
Similarity:
Belongs to the tumor necrosis factor family.
SWISS:
O75888
Gene ID:
8741
Database links:Entrez Gene: 8741 Human
Entrez Gene: 69583 Mouse
Omim: 604472 Human
SwissProt: O75888 Human
SwissProt: Q9D777 Mouse
Unigene: 54673 Human
Unigene: 8983 Mouse
Unigene: 19955 Rat
Product Picture Blank control(blue): Jurkat cells(fixed with 2% paraformaldehyde (10 min)).
Primary Antibody:Rabbit Anti-APRIL/TNFSF13 antibody(SL5725R), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions );
Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
Scan Wechat Qrcode