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Product Name GDF10 Chinese Name 生长分化因子10抗体 Alias BIP; BMP 3b; BMP3B; Bone inducing protein; Bone morphogenetic protein 3b; GDF 10; GDF-10; growth differentiation factor 10; BMP3B_HUMAN; Bone-inducing protein; Growth/differentiation factor 10. literatures Specific References (1) | SL5720R has been referenced in 1 publications.[IF=15.266] Armaka, Marietta. et al. Single-cell multimodal analysis identifies common regulatory programs in synovial fibroblasts of rheumatoid arthritis patients and modeled TNF-driven arthritis. GENOME MED. 2022 Dec;14(1):1-25 IF ; Mouse.Research Area Tumour immunology Signal transduction Stem cells Cyclin transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, Pig, Horse, Guinea Pig, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 12kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GDF10: 371-478/478 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail GDF10, or growth differentiation factor 10, bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. GDF10 is expressed in femur, brain, lung, skeletal muscle, pancreas and testis.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in femur, brain, lung, skeletal muscle, pancreas and testis.
Similarity:
Belongs to the TGF-beta family.
SWISS:
P55107
Gene ID:
2662
Database links:Entrez Gene: 2662 Human
Entrez Gene: 14560 Mouse
GenBank: NM_004962 Human
Omim: 601361 Human
SwissProt: P55107 Human
SwissProt: P97737 Mouse
Unigene: 2171 Human
Unigene: 432071 Mouse
Product Picture Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GDF10) Polyclonal Antibody, Unconjugated (SL5720R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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