TEL: +86 571 56623320 EMAIL: [email protected]
Product Name NCOA2 Chinese Name 类固醇受体激活蛋白2抗体 Alias glucocorticoid receptor interacting protein 1; GRIP 1; GRIP1; MED1; MGC138808; NCoA 2; nuclear receptor coactivator 2; Oncogene FGR; p160; SRC 2; src2; Steroid receptor coactivator 2; TIF 2; TIF2; Transcriptional intermediary factor 2; NCOA2_HUMAN. Research Area Tumour Signal transduction Apoptosis transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:500-2000 IHC-P=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 159kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen Recombinant human NCOA2: 550-820/1424 Lsotype IgG Purification affinity purified by Protein A Buffer Solution PBS with 0.02% sodium azide,50% glycerol,pH7.3. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcriptional activity of the nuclear receptor with which they associate. One such coactivator is KAT13C / nuclear receptor coactivator 2 (NCOA2), also termed Glucocorticoid receptor-interacting protein 1 (GRIP1).
Subcellular Location:
Nucleus.
Similarity:
Belongs to the SRC/p160 nuclear receptor coactivator family.
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 PAS (PER-ARNT-SIM) domain.
SWISS:
Q15596
Gene ID:
10499
Database links:Entrez Gene: 10499 Human
Omim: 601993 Human
SwissProt: Q15596 Human
Unigene: 446678 Human
Scan Wechat Qrcode