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Product Name phospho-JunD (Ser255) Chinese Name 磷酸化活化蛋白激酶D抗体 Alias JunD (phospho S255); JunD (Phospho Ser255); Transcription factor jun-D; jun D proto-oncogene; JUND1; AP-1; JUND; JUND1; MGC6245; MGC72300; AP 1; AP1; jun D proto oncogene; JunD FL isoform; JUND_HUMAN; Transcription factor jun D; transcription factor jun-D isoform JunD-FL; Jun-like transcription factor; pfam03957. Product Type Phosphorylated anti Research Area Tumour immunology Signal transduction transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Chicken, Dog, Cow, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 38kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated Synthesised phosphopeptide derived from human JunD around the phosphorylation site of Ser255: GE(p-S)PP Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Function:
Transcription factor binding AP-1 sites.
Subunit:
Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.
SWISS:
P17535
Gene ID:
3727
Database links:Entrez Gene: 3727 Human
Entrez Gene: 16478 Mouse
Omim: 165162 Human
SwissProt: P17535 Human
SwissProt: P15066 Mouse
Unigene: 2780 Human
Unigene: 419851 Mouse
Unigene: 46225 Rat
Jun-D属于转录因子AP-1家族(Jun蛋白家族包括c-Jun、JunB和JunD)
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