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Rabbit Anti-phospho-JunD (Ser255)antibody
Rabbit Anti-phospho-JunD (Ser255)antibody
JunD (phospho S255); JunD (Phospho Ser255); Transcription factor jun-D; jun D proto-oncogene; JUND1; AP-1; JUND; JUND1; MGC6245; MGC72300; AP 1; AP1; jun D proto oncogene; JunD FL isoform; JUND_HUMAN; Transcription factor jun D; transcription factor jun-D
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Product Name phospho-JunD (Ser255)
Chinese Name 磷酸化活化蛋白激酶D抗体
Alias JunD (phospho S255); JunD (Phospho Ser255); Transcription factor jun-D; jun D proto-oncogene; JUND1; AP-1; JUND; JUND1; MGC6245; MGC72300; AP 1; AP1; jun D proto oncogene; JunD FL isoform; JUND_HUMAN; Transcription factor jun D; transcription factor jun-D isoform JunD-FL; Jun-like transcription factor; pfam03957.  
Product Type Phosphorylated anti 
Research Area Tumour  immunology  Signal transduction  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Chicken, Dog, Cow, )
Applications ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 38kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated Synthesised phosphopeptide derived from human JunD around the phosphorylation site of Ser255: GE(p-S)PP 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.

Function:
Transcription factor binding AP-1 sites.

Subunit:
Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.

SWISS:
P17535

Gene ID:
3727

Database links:

Entrez Gene: 3727 Human

Entrez Gene: 16478 Mouse

Entrez Gene: 24518 Rat

Omim: 165162 Human

SwissProt: P17535 Human

SwissProt: P15066 Mouse

SwissProt: P52909 Rat

Unigene: 2780 Human

Unigene: 419851 Mouse

Unigene: 46225 Rat



Jun-D属于转录因子AP-1家族(Jun蛋白家族包括c-Jun、JunB和JunD)

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