Product Name	phospho-MAP4 (Ser941)
Chinese Name	磷酸化微管相关蛋白4抗体
Alias	MAP4 (phospho S941); p-MAP4 (phospho S941); MAP4(phospho Ser941); DKFZp779A1753; MAP-4; MAP4; MAP4_HUMAN; MGC8617; Microtubule associated protein 4; Microtubule-associated protein 4; OTTHUMP00000210723; OTTHUMP00000210725; OTTHUMP00000210727; OTTHUMP00000210730.
Product Type	Phosphorylated anti
Research Area	Cell biology  Signal transduction  Cyclin  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	121kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated Synthesised phosphopeptide derived from human MAP4 around the phosphorylation site of Ser941: VG(p-S)TE
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly. Function: Non-neuronal microtubule-associated protein. Promotes microtubule assembly. Subunit: Interacts with SEPT2; this interaction impedes tubulin-binding. Subcellular Location: Cytoplasm, cytoskeleton. Post-translational modifications: Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Phosphorylation on Ser-787 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 3 is phosphorylated on Ser-337 and Ser-338. Similarity: Contains 4 Tau/MAP repeats. SWISS: P27816 Gene ID: 4134 Database links: Entrez Gene: 4134 Human Entrez Gene: 17758 Mouse Entrez Gene: 367171 Rat Omim: 157132 Human SwissProt: P27816 Human SwissProt: P27546 Mouse SwissProt: Q5M7W5 Rat Unigene: 517949 Human Unigene: 217318 Mouse Unigene: 443428 Mouse Unigene: 484451 Mouse Unigene: 203122 Rat

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