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Rabbit Anti-phospho-LSP1 (Ser252)antibody
Rabbit Anti-phospho-LSP1 (Ser252)antibody
LSP1 (phospho S252); p-LSP1 (phospho S252); 47 kDa actin binding protein; 47 kDa actin-binding protein; 52 kDa phosphoprotein; F actin binding and cytoskeleton associated protein; Leufactin (leukocyte F-actin binding protein); Leufactin; Leukocyte F actin
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Product Name phospho-LSP1 (Ser252)
Chinese Name 磷酸化白细胞F肌动蛋白Binding protein抗体
Alias LSP1 (phospho S252); p-LSP1 (phospho S252); 47 kDa actin binding protein; 47 kDa actin-binding protein; 52 kDa phosphoprotein; F actin binding and cytoskeleton associated protein; Leufactin (leukocyte F-actin binding protein); Leufactin; Leukocyte F actin binding protein; Leukocyte specific protein 1; LSP 1; Lsp1; LSP1_HUMAN; Lymphocyte specific antigen WP34; Lymphocyte specific protein 1; Lymphocyte specific protein pp52; Lymphocyte-specific antigen WP34; Lymphocyte-specific protein 1; OTTHUMP00000014138; OTTHUMP00000014139; OTTHUMP00000014140; OTTHUMP00000069612; OTTHUMP00000069614; OTTHUMP00000069615; OTTHUMP00000069616; pp52; Protein pp52; S37 protein; WP 34; WP34.   
Product Type Phosphorylated anti 
Research Area Cell biology  immunology  Signal transduction  Binding protein  lymphocyte  t-lymphocyte  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 37kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated Synthesised phosphopeptide derived from human LSP1 around the phosphorylation site of Ser252: QA(P-S)IE 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail May play a role in mediating neutrophil activation and chemotaxis.

Function:
May play a role in mediating neutrophil activation and chemotaxis (By similarity).

Subunit:
Binds actin.

Subcellular Location:
Cell membrane; Peripheral membrane protein; Cytoplasmic side.

Tissue Specificity:
Activated T-lymphocytes.

Post-translational modifications:
Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis (By similarity).

SWISS:
P33241

Gene ID:
4046

Database links:

Entrez Gene: 4046 Human

Entrez Gene: 16985 Mouse

Entrez Gene: 361680 Rat

Omim: 153432 Human

SwissProt: P33241 Human

SwissProt: P19973 Mouse

Unigene: 56729 Human

Unigene: 234003 Mouse

Unigene: 101608 Rat



Product Picture
Sample: Lovo Cell (Human) Lysate at 30 ug
Primary: Anti-p-LSP1(Ser252) (SL5156R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37kD
Observed band size: 40kD

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