Product Name	Bacillus anthraci protein
Chinese Name	炭疽杆菌菌体蛋白抗体
Alias	Bacillus anthracis cell protein;
Research Area	immunology  Bacteria and viruses
Immunogen Species	Rabbit
Clonality	Polyclonal
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Liquid
Concentration	1mg/ml
immunogen	Whole cell protein of Bacillus anthraci
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Bacillus anthracis is an aerobic spore forming bacterium that causes anthrax, an acute infectious disease of cattle, sheep, goats, camels, antelopes and other herbivores. Infection can occur in humans when they are exposed to infected animals or tissue from infected animals via three routes: cutaneous, inhalation and gastrointestinal. B. anthracis spores persist in the soil for many years as they are resistant to heat, cold, radiation, desiccation, and disinfectants. In vivo, B anthracis produces a polypeptide (polyglutamic acid) capsule that protects it from phagocytosis. The virulence factors of B anthracis are its capsule and three component toxin, both encoded on plasmids. SWISS: N/A Gene ID: N/A 炭疽杆菌从损伤的皮肤、胃肠粘膜及呼吸道进入人体后，首先在局部繁殖，产生毒素而致组织及脏器发生出血性浸润、坏死和高度水肿，形成原发性皮肤炭疽、肠炭疽的肺炭疽等。当机体抵抗力降低时，致病菌即迅速沿淋巴管及血管向全身扩散，形成败血症和继发性脑膜炎。皮肤炭疽因缺血及毒素的作用，真皮的神经纤维发生变化，故病灶处常无明显的疼痛感。炭疽杆菌的毒素可直接损伤血管的endothelial cells，使血管壁的通透性增加，导致有效血容量减少，微循环灌注量下降，血液呈高凝状态，出现DIC和感染性休克。

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