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Rabbit Anti-NPTX1 antibody
Rabbit Anti-NPTX1 antibody
Neuronal pentraxin I; Neuronal pentraxin-1; NP 1; NP-I; NP1; Nptx1; NPTX1_HUMAN.
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  • NO.:SL4893R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
  • Goods click count:29
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Details

Product Name NPTX1
Chinese Name 神经细胞正五聚体1抗体
Alias Neuronal pentraxin I; Neuronal pentraxin-1; NP 1; NP-I; NP1; Nptx1; NPTX1_HUMAN.   
literatures
Specific References  (1)     |     SL4893R has been referenced in 1 publications.
[IF=2.967] Jing Wu. et al. NPTX1 inhibits pancreatic cancer cell proliferation and migration and enhances chemotherapy sensitivity by targeting RBM10. Oncol Lett. 2022 May;23(5):1-9  WB ;  Human.  
Research Area immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 45kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NPTX1: 201-300/432 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.

Function:
May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle (Potential).

Similarity:
Contains 1 pentaxin domain.

SWISS:
Q15818

Gene ID:
4884

Database links:

Entrez Gene: 4884 Human

Entrez Gene: 18164 Mouse

Entrez Gene: 266777 Rat

Omim: 602367 Human

SwissProt: Q15818 Human

SwissProt: Q62443 Mouse

SwissProt: P47971 Rat

Unigene: 514556 Human

Unigene: 719680 Human

Unigene: 5142 Mouse

Unigene: 54707 Rat



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