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Rabbit Anti-TACI antibody
Rabbit Anti-TACI antibody
TACI; CD267; CD267 antigen; CVID; TNFRSF 13B; TNFRSF 14B;TNFRSF13B; TNFRSF13B protein; TNFRSF14B; Transmembrane activator and CAML interactor; Tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B.
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Details

Product Name TACI
Chinese Name Tumour坏死因子受体超家族成员13B抗体
Alias TACI; CD267; CD267 antigen; CVID; TNFRSF 13B; TNFRSF 14B;TNFRSF13B; TNFRSF13B protein; TNFRSF14B; Transmembrane activator and CAML interactor; Tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B.   
Research Area Cell biology  immunology  lymphocyte  t-lymphocyte  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 32kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human TNFRSF13B/CD267/TACI : 21-120/293 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.

Subcellular Location:
Membrane; Single-pass type III membrane protein.

Tissue Specificity:
Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.

Similarity:
Contains 2 TNFR-Cys repeats.

SWISS:
O14836

Gene ID:
23495

Database links:

Entrez Gene: 23495 Human

Entrez Gene: 57916 Mouse

Omim: 604907 Human

SwissProt: O14836 Human

SwissProt: Q9ET35 Mouse

Unigene: 158341 Human

Unigene: 265915 Mouse



Product Picture
Sample:
Spleen (Mouse) Lysate at 40 ug
Primary: Anti- TACI (SL4841R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 30 kD

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