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Rabbit Anti-Endomucin antibody
Rabbit Anti-Endomucin antibody
EMCN; EMCN2; Endomucin 2; Endomucin; Endomucin-2; Endothelial sialomucin; Gastric cancer antigen Ga34; MUC-14; MUCEN_HUMAN; Mucin 14; Mucin-14.
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Details

Product Name Endomucin
Chinese Name 内皮粘蛋白EMCN抗体
Alias EMCN; EMCN2; Endomucin 2; Endomucin; Endomucin-2; Endothelial sialomucin; Gastric cancer antigen Ga34; MUC-14; MUCEN_HUMAN; Mucin 14; Mucin-14.  
Research Area Tumour  immunology  Signal transduction  glycoprotein  Cytoskeleton  Extracellular matrix  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 25kDa
Cellular localization The cell membrane Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Endomucin: 21-120/261 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.

Function:
Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.
Isoform 2: Secreted (Potential).

Tissue Specificity:
Expressed in heart, kidney and lung.

Post-translational modifications:
Highly O-glycosylated. Sialic acid-rich glycoprotein.

SWISS:
Q9ULC0

Gene ID:
51705

Database links:

Entrez Gene: 51705 Human

Omim: 608350 Human

SwissProt: Q9ULC0 Human

Unigene: 152913 Human



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