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Product Name Endomucin Chinese Name 内皮粘蛋白EMCN抗体 Alias EMCN; EMCN2; Endomucin 2; Endomucin; Endomucin-2; Endothelial sialomucin; Gastric cancer antigen Ga34; MUC-14; MUCEN_HUMAN; Mucin 14; Mucin-14. Research Area Tumour immunology Signal transduction glycoprotein Cytoskeleton Extracellular matrix Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 25kDa Cellular localization The cell membrane Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Endomucin: 21-120/261 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Function:
Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.
Isoform 2: Secreted (Potential).
Tissue Specificity:
Expressed in heart, kidney and lung.
Post-translational modifications:
Highly O-glycosylated. Sialic acid-rich glycoprotein.
SWISS:
Q9ULC0
Gene ID:
51705
Database links:Entrez Gene: 51705 Human
Omim: 608350 Human
SwissProt: Q9ULC0 Human
Unigene: 152913 Human
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