Product Name	CK15
Chinese Name	细胞角蛋白15抗体
Alias	K1C15_HUMAN; Cytokeratin 15; CK 15; CK15; Cytokeratin15; K15; K1CO; Keratin 15; Keratin 15 basic; Keratin 15 beta; Keratin complex 1 acidic gene 15; Keratin type I cytoskeletal 15; Keratin15; KRT 15; KRTB; KRTL15; keratin-15, basic; Type I cytoskeletal 15.
literatures	Specific References  (3)     |     SL4762R has been referenced in 3 publications. [IF=2.792] Yan, Wei. et al. Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats. BMC VET RES. 2022 Dec;18(1):1-18  IF, WB ;  Goat.   PubMed:35971123 [IF=1.92] Li et al. miR‑339‑5p negatively regulates loureirin A‑induced hair follicle stem cell differentiation by targeting DLX5. (2018) Mol.Med.Rep. 18:1279-1286  ICC ;  Rat.   PubMed:29901112 [IF=1.329] Ziwei Luo. et al. miR‐203a‐3p promotes loureirin A‐induced hair follicle stem cells differentiation by targeting Smad1. Anat Rec. 2021 Mar;304(3):531-540  IF ;  Rat.   PubMed:32589363
Research Area	Cell biology  immunology  Signal transduction  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	49kDa
Cellular localization	The nucleus cytoplasmic Extracellular matrix Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CK15: 351-456/456
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq, Jul 2008]. Subunit: Heterotetramer of two type I and two type II keratins. Tissue Specificity: Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate. Similarity: Belongs to the intermediate filament family. SWISS: P19012 Gene ID: 3866 Database links: Entrez Gene: 3866 Human Entrez Gene: 16665 Mouse Entrez Gene: 287700 Rat Omim: 148030 Human SwissProt: P19012 Human SwissProt: Q61414 Mouse SwissProt: Q6IFV3 Rat Unigene: 654570 Human Unigene: 440010 Mouse Unigene: 153568 Rat
Product Picture	Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti- CK15 (SL4762R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD

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