Product Name	PILRB
Chinese Name	细胞表面受体PILRβ抗体
Alias	PILR beta; Paired immunoglobulin-like type 2 receptor beta; Activating receptor PILR beta; Cell surface receptor FDFACT; Cell surface receptor FDFACT1; Cell surface receptor FDFACT2; FDFACT; FDFACT1; FDFACT2; PILRB; Paired immunoglobulin like receptor beta; Paired immunoglobulin like type 2 receptor beta; Paired immunoglobulin like type 2 receptor beta precursor.
Research Area	Signal transduction  Stem cells  The cell membrane受体  Cell Surface Molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	23kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse PILR beta: 51-150/224 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: Q2YFS2 Gene ID: 170741 Database links: Entrez Gene: 29990 Human Omim: 605342 Human SwissProt: Q9UKJ0 Human Unigene: 632314 Human Ⅱ型成对免疫球蛋白样受体β蛋白

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