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Rabbit Anti-PTCD1 antibody
Rabbit Anti-PTCD1 antibody
Pentatricopeptide repeat containing protein 1; Pentatricopeptide repeat domain 1; Pentatricopeptide repeat-containing protein 1; PTCD1; PTCD1_HUMAN.
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  • NO.:SL4423R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name PTCD1
Chinese Name PTCD1蛋白抗体
Alias Pentatricopeptide repeat containing protein 1; Pentatricopeptide repeat domain 1; Pentatricopeptide repeat-containing protein 1; PTCD1; PTCD1_HUMAN.  
Research Area Cell biology  Developmental biology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 79kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PTCD1: 601-700/700 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a mitochondrial protein that binds leucine tRNAs and other mitochondrial RNAs and plays a role in the regulation of translation. Increased expression of this gene results in decreased mitochondrial leucine tRNA levels. Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2) and this gene. [provided by RefSeq, Aug 2015]

Function:
Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs

Subunit:
Associates with mitochondrial leucine tRNAs. Interacts with ELAC2.

Tissue Specificity:
Abundant in testes, skeletal muscle and heart.

Similarity:
Belongs to the PTCD1 family.
Contains 9 PPR (pentatricopeptide) repeats.

SWISS:
O75127

Gene ID:
26024

Database links:

Entrez Gene: 26024 Human

Omim: 614774 Human

SwissProt: O75127 Human

Unigene: 632313 Human



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