Product Name	ZMIZ2
Chinese Name	锌指MIZ结构域蛋白2抗体
Alias	2410117E06Rik; D11Bwg0280e; DKFZp761I2123; hZIMP7; KIAA1886; PIAS like protein Zimp7; PIAS-like protein Zimp7; R74931; RGD1309256; RP23-198N14.8; ZIMP7; Zinc finger MIZ domain containing protein 2; Zinc finger MIZ domain-containing protein 2; Zinc finger MIZ type containing 2; zinc finger, MIZ-type containing 2; zinc finger, MIZtype containing2; ZMIZ 2; Zmiz2; ZMIZ2_HUMAN.
Research Area	transcriptional regulatory factor  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Rabbit, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	97kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZMIZ2: 1-100/920
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010] Function: Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. Subcellular Location: Nucleus. Detected at replication foci throughout S phase. Tissue Specificity: Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary. Similarity: Contains 1 SP-RING-type zinc finger. SWISS: Q8NF64 Gene ID: 83637 Database links: Entrez Gene: 83637 Human Entrez Gene: 52915 Mouse Entrez Gene: 289783 Rat Entrez Gene: 6378 Rat Omim: 611196 Human SwissProt: Q8NF64 Human SwissProt: Q8CIE2 Mouse Unigene: 600681 Human Unigene: 77978 Human Unigene: 1144 Mouse
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZMIZ2) Polyclonal Antibody, Unconjugated (SL4391R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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