Product Name	ZNF769/RB associated KRAB repressor
Chinese Name	Zinc finger protein769抗体
Alias	RB associated KRAB repressor; hRBaK; Hypothetical protein RBAK; RB associated KRAB zinc finger; RB-associated KRAB repressor; RB-associated KRAB zinc finger protein; RBAK; RBAK_HUMAN; Zinc finger protein 769; ZNF 769; ZNF769.
Research Area	transcriptional regulatory factor  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Dog, Pig, Cow, Horse, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	83kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZNF769: 251-350/714
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011] Function: May repress E2F-dependent transcription. May promote AR-dependent transcription. Subcellular Location: Nucleus. Tissue Specificity: Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 16 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: Q9NYW8 Gene ID: 57786 Database links: Entrez Gene: 57786 Human Entrez Gene: 57782 Mouse Omim: 608191 Mouse SwissProt: Q9NYW8 Human SwissProt: Q8BQC8 Mouse Unigene: 396178 Human Unigene: 320419 Mouse

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