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Product Name ZNF653 Chinese Name Zinc finger protein653抗体 Alias 67 kDa zinc finger protein; Zinc finger protein 653; Zinc finger protein Zip67; ZIP67; ZN653_HUMAN; Znf653. Research Area transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 67kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZNF653: 51-150/615 Lsotype IgG Purification affinity purified by Protein A Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ZNF653 (Zinc Finger Protein 653) is a Protein Coding gene. An important paralog of this gene is ENSG00000267477.
Function:
Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity.
Subcellular Location:
Nucleus.
Tissue Specificity:
Highly expressed in testis, cerebellum, temporal lobe, hippocampus and the adrenal gland. Moderately expressed in spleen, uterus, thymus, pancreas, kidney, stomach and rectum.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.
SWISS:
Q96CK0
Gene ID:
115950
Database links:Entrez Gene: 115950 Human
Omim: 611371 Human
SwissProt: Q96CK0 Human
Unigene: 465928 Human
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