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Product Name CDC40 Chinese Name 细胞分裂周期同源蛋白40抗体 Alias Cell division cycle 40 homolog; EH binding protein 3; Ehb3; Pre mRNA processing factor 17; PRP17; PRP17 homolog; PRPF17; PRP17_HUMAN; Pre-mRNA-processing factor 17; EH-binding protein 3; hPRP17. Research Area Tumour Cell biology immunology Chromatin and nuclear signals Cyclin Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 66kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CDC40: 481-579/579 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]
Function:
Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.
Subunit:
Identified in the spliceosome C complex.
Subcellular Location:
Nucleus.
Similarity:
Contains 7 WD repeats.
SWISS:
O60508
Gene ID:
51362
Database links:Entrez Gene: 51362 Human
Entrez Gene: 71713 Mouse
Omim: 605585 Human
SwissProt: O60508 Human
SwissProt: Q9DC48 Mouse
Unigene: 428147 Human
Unigene: 46063 Mouse
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