Product Name	cIAP1
Chinese Name	凋亡抑制因子1抗体
Alias	API 1; API1; Apoptosis inhibitor 1; Baculoviral IAP repeat containing 2; Baculoviral IAP repeat containing protein 2; Baculoviral IAP repeat-containing protein 2; BIRC 2; BIRC2; BIRC2_HUMAN; C IAP1; C-IAP1; cIAP 1; HIAP 2; HIAP-2; HIAP2; IAP 2; IAP homolog B; IAP-2; IAP2; Inhibitor of apoptosis protein 2; MIHB; NFR2 TRAF signalling complex protein; RING finger protein 48; RNF 48; RNF48; TNFR2 TRAF signaling complex protein 2; TNFR2-TRAF-signaling complex protein 2.
literatures	Specific References  (3)     |     SL4262R has been referenced in 3 publications. [IF=5.988] He Shanqing. et al. Dapagliflozin Protects Methamphetamine-Induced Cardiomyopathy by Alleviating Mitochondrial Damage and Reducing Cardiac Function Decline in a Mouse Model. FRONT PHARMACOL. 2022 Jul;0:2578  WB ;  Mouse.   PubMed:35873593 [IF=2.91] Sun et al. Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer. (2015) J.Bioenerg.Biomembr. 47:319-29  WB ;  Mouse.   PubMed:26054380 [IF=1.69] Xuan et al. Short?term vagus nerve stimulation reduces myocardial apoptosis by downregulating microRNA?205 in rats with chronic heart failure. (2017) Mol.Med.Rep. 16:5847-5854  WB ;  Rat.   PubMed:28849082
Research Area	Tumour  Cell biology  immunology  Apoptosis
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	72kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human cIAP1: 51-150/618
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). SWISS: Q13490 Gene ID: 329 Database links: Entrez Gene: 329 Human Entrez Gene: 11797 Mouse Entrez Gene: 60371 Rat Omim: 601712 Human SwissProt: Q13490 Human SwissProt: Q62210 Mouse Unigene: 696238 Human Unigene: 335659 Mouse Unigene: 205955 Rat
Product Picture	Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti- cIAP1 (SL4262R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 72 kD Observed band size: 72 kD Paraformaldehyde-fixed, paraffin embedded (mouse testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (cIAP1) Polyclonal Antibody, Unconjugated (SL4262R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining. Paraformaldehyde-fixed, paraffin embedded (rat heart tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (cIAP1) Polyclonal Antibody, Unconjugated (SL4262R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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