Product Name	P2X3
Chinese Name	三磷酸腺苷受体受体P2X3抗体
Alias	ATP receptor; ATP receptor; MGC129956; P2RX3; P2RX3_HUMAN; P2X purinoceptor 3; P2X receptor subunit 3; P2X3; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 3; Purinergic receptor P2X3; Purinoceptor P2X3.
Research Area	Tumour  immunology  Neurobiology  Channel protein  The cell membrane受体
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Pig, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	44kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human P2X3: 241-340/397
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	P2RX3 is a member of the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and transduces ATP-evoked nociceptor activation. P2RX3 is important for peripheral pain responses, and controls urinary bladder volume reflexes. Function: Receptor for ATP that acts as a ligand-gated ion channel. Subunit: Homo- or heteropolymers. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the P2X receptor family. SWISS: P56373 Gene ID: 5024 Database links: Entrez Gene: 5024 Human Entrez Gene: 228139 Mouse Entrez Gene: 81739 Rat Omim: 600843 Human SwissProt: P56373 Human SwissProt: Q3UR32 Mouse SwissProt: P49654 Rat Unigene: 146738 Human Unigene: 440375 Mouse Unigene: 448935 Mouse Unigene: 10388 Rat
Product Picture	Blank control: U87MG. Primary Antibody (green line): Rabbit Anti-P2X3 antibody (SL4249R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.

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