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Product Name SARS-CoV-2 N protein Chinese Name SARS冠状病毒2核衣壳蛋白抗体 Alias SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Protein; 2019 ncov N Protein; 2019-nCoV nucleocapsid protein. literatures Specific References (4) | SL41408R has been referenced in 4 publications.[IF=6.107] Christina Wenzek. et al. CD47 restricts antiviral function of alveolar macrophages during influenza virus infection. ISCIENCE. 2022 Nov;:105540 ELISA ; Monkey.[IF=5.125] Anissa Viveiros. et al. SARS-CoV-2 Infection Downregulates Myocardial ACE2 and Potentiates Cardiac Inflammation in Humans and Hamsters. AM J PHYSIOL-HEART C. 2022 Nov;(Articles in Press): IHC ; Hamster.[IF=5.075] Yuting Wu. et al. Construction, Characterization, and Application of a Nonpathogenic Virus-like Model for SARS-CoV-2 Nucleocapsid Protein by Phage Display. TOXINS. 2022 Oct;14(10):683 WB ; Other.[IF=4.501] Aleksandra Milewska. et al. HTCC as a Polymeric Inhibitor of SARS-CoV-2 and MERS-CoV. J Virol. 2021 Jan;95(4):e01622-20 WB ; Human.Immunogen Species Rabbit Clonality Polyclonal Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 46kDa Form Liquid Concentration ≥1mg/ml immunogen Recombinant SARS-CoV-2 Nucleocapsid Protein Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
SWISS:
P0DTC9
Gene ID:
43740575
Product Picture Sample:
Lane 1: SARS-CoV N protein(Cat# SL49002P) at 50ng
Lane 2: SARS-CoV N protein(Cat# SL49002P) at 25ng
Lane 3: SARS-CoV N protein(Cat# SL49002P) at 15ng
Lane 4: SARS-CoV N protein(Cat# SL49002P) at 10ng
Lane 5: SARS-CoV N protein(Cat# SL49002P) at 5ng
Lane 6: SARS-CoV N protein(Cat# SL49002P) at 2.5ng
Lane 7: SARS-CoV-2 N protein(Cat# SL41408P) at 50ng
Lane 8: SARS-CoV-2 N protein(Cat# SL41408P) at 25ng
Lane 9: SARS-CoV-2 N protein(Cat# SL41408P) at 15ng
Lane 10: SARS-CoV-2 N protein(Cat# SL41408P) at 10ng
Lane 11: SARS-CoV-2 N protein(Cat# SL41408P) at 5ng
Lane 12:SARS-CoV-2 N protein(Cat# SL41408P) at 2.5ng
Primary: Anti- SARS-CoV-2 N protein (SL41408R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
Sample:
Lane 1: SARS-CoV-2 N protein(Cat# SL41408P) at 50ng
Lane 2: SARS-CoV-2 N protein(Cat# SL41408P) at 25ng
Lane 3: SARS-CoV-2 N protein(Cat# SL41408P) at 15ng
Lane 4: SARS-CoV-2 N protein(Cat# SL41408P) at 10ng
Lane 5: SARS-CoV-2 N protein(Cat# SL41408P) at 5ng
Lane 6:SARS-CoV-2 N protein(Cat# SL41408P) at 2.5ng
Primary: Anti- SARS-CoV-2 N protein (SL41408R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
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