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Product Name SNX25 Chinese Name 分拣微管连接蛋白抗体 Alias SBBI31; Sorting nexin-25; AI661919; FLJ23161; Gm1699; Gm173; MSTP043; SNX25; SNX25_HUMAN. Research Area immunology Signal transduction transcriptional regulatory factor Binding protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 98kDa Cellular localization cytoplasmic The cell membrane Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SNX25: 521-620/840 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNX25 (sorting nexin 25), also known as SBBI31 or MSTP043, is an 840 amino acid protein suggested to function in several stages of intracellular trafficking. A member of the sorting nexin family, SNX25 contains one PX (phox homology) domain, an RGS domain and one PXA domain.
Function:
May be involved in several stages of intracellular trafficking
Subcellular Location:
Endosome membrane; Peripheral membrane protein. Note=Detected in endosome-derived secreted vesicles (exosomes) from malignant pleural effusions.
Similarity:
Belongs to the sorting nexin family.
Contains 1 PX (phox homology) domain.
Contains 1 PXA domain.
Contains 1 RGS domain.
SWISS:
Q9H3E2
Gene ID:
83891
Database links:Entrez Gene: 83891 Human
Entrez Gene: 102141 Mouse
SwissProt: Q9H3E2 Human
SwissProt: Q3ZT31 Mouse
Unigene: 369091 Human
Unigene: 267258 Mouse
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