Product Name	MAT2A
Chinese Name	蛋氨酸腺苷转移酶抗体
Alias	MAT2A AdoMet synthetase 2; AdoMet synthetase; AMS 2; AMS2; MAT 2A; MAT II; MATA 2; MATA2; MATII; Methionine adenosyltransferase 2; Methionine adenosyltransferase; Methionine adenosyltransferase II alpha; Methionine adenosyltransferase II; S adenosylmethionine synthetase gamma form; S adenosylmethionine synthetase isoform type 2; SAMS 2; SAMS2; METK1_HUMAN.
literatures	Specific References  (2)     |     SL4054R has been referenced in 2 publications. [IF=4.966] Li Chen. et al. Activating transcription factor 4 regulates angiogenesis under lipid overload via methionine adenosyltransferase 2A‐mediated endothelial epigenetic alteration. Faseb J. 2021 Jun;35(6):e21612  IHC ;  Mouse.   PubMed:33948996 [IF=4.181] Chen et al. Metabolomic analysis reveals metabolic changes caused by bisphenol A in rats. (2014) Toxicol.Sci. 138:256-67  WB ;  Rat.   PubMed:24449424
Research Area	Cell biology  immunology  Signal transduction  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Zebrafish, Monkey, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	44kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Methionine adenosyltransferase: 31-130/395
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	S adenosylmethionine synthetase catalyzes the formation of S adenosylmethionine from methionine and ATP. In mammalian tissues, there are three distinct forms of AdoMet synthases designated as alpha, beta, and gamma. Alpha and beta are expressed only in adult liver, while gamma is widely distributed in extrahepatic tissues. Function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. Subunit: Homotetramer (MAT-I) or homodimer (MAT-III). Tissue Specificity: Expressed in liver. Post-translational modifications: S-nitrosylation of Cys-120 inactivates the enzyme (By similarity). DISEASE: Defects in MAT1A are the cause of methionine adenosyltransferase deficiency (MATD) [MIM:250850]; also called MAT I/III deficiency. MATD is an inborn error of metabolism resulting in isolated hypermethioninemia. Most patients have no clinical abnormalities, although some neurologic symptoms may be present in rare cases with severe loss of methionine adenosyltransferase activity. Similarity: Belongs to the AdoMet synthase family. SWISS: P31153 Gene ID: 4144 Database links: Entrez Gene: 459363 Chimpanzee Entrez Gene: 101865874 Cynomolgus Monkey Entrez Gene: 475770 Dog Entrez Gene: 4144 Human Entrez Gene: 232087 Mouse Entrez Gene: 171347 Rat Entrez Gene: 695362 Rhesus monkey Entrez Gene: 323329 Zebrafish Omim: 601468 Human SwissProt: Q4R924 Cynomolgus Monkey SwissProt: P31153 Human SwissProt: Q3THS6 Mouse SwissProt: Q5R5H1 Orangutan SwissProt: P18298 Rat Unigene: 516157 Human Unigene: 29815 Mouse Unigene: 485037 Mouse Unigene: 144658 Rat Unigene: 41420 Rat

Cartpieces

• 
• 1

  1Delete

• 
• 5

  5Delete

• 
• S

  SDelete

• 
• R

  RDelete

• 
• +

  +Delete

• 
• 3

  3Delete

• Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• M

  MDelete

• 
• M

  MDelete

• 

• Delete

• 
• i

  iDelete

• 
• i

  iDelete

• Delete

• 
• 1

  1Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• Delete

• 
• 2

  2Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• Delete

• 
• -

  -Delete

• 
• -

  -Delete

• 
• 0

  0Delete

• Delete

• 
• t

  tDelete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• f

  fDelete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• Delete

• 
• 0

  0Delete

• Delete

• Delete

• Delete

• 
• R

  RDelete

• 
• 5

  5Delete

• 
• A

  ADelete

Totalgoods,subtotals:￥Checkout