Product Name	Ketohexokinase
Chinese Name	肝果糖激酶抗体
Alias	fructokinase; Hepatic fructokinase; ketohexokinase; Ketohexokinase isoform a; KHK; EC 2.7.1.3; KHK_HUMAN.
Research Area	Tumour  Cell biology  immunology  transcriptional regulatory factor  Kinases and Phosphatases  glycoprotein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	33kDa
Cellular localization	cytoplasmic Extracellular matrix
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Ketohexokinase: 151-250/298
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Subunit: Homodimer. Tissue Specificity: Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye. DISEASE: Defects in KHK are the cause of fructosuria (FRUCT) [MIM:229800]. Benign defect of intermediary metabolism. Similarity: Belongs to the carbohydrate kinase PfkB family. SWISS: P50053 Gene ID: 3795 Database links: Entrez Gene: 3795 Human Entrez Gene: 16548 Mouse Omim: 614058 Human SwissProt: P50053 Human SwissProt: Q6IBK2 Human SwissProt: P97328 Mouse Unigene: 567297 Human Unigene: 22451 Mouse

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