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Product Name SLC25A11 Chinese Name Mitochondrion二羧酸载体蛋白11抗体 Alias Mitochondrial 2 oxoglutarate/malate carrier protein; OGC; OGCP; SLC20A4; Solute carrier family 20 (oxoglutarate carrier) member 4; Solute carrier family 20 member 4; Solute carrier family 25 (mitochondrial carrier oxoglutarate carrier) member 11; Solute carrier family 25 member 11. Research Area Tumour Cell biology immunology transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 34kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC25A11: 35-140/314 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
Function:
Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.
Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
SWISS:
Q02978
Gene ID:
8402
Database links:Entrez Gene: 8402 Human
Entrez Gene: 67863 Mouse
Omim: 604165 Human
SwissProt: Q02978 Human
SwissProt: Q9CR62 Mouse
Unigene: 184877 Human
Unigene: 296082 Mouse
Unigene: 466994 Mouse
Unigene: 853 Rat
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