TEL: +86 571 56623320 EMAIL: [email protected]
Product Name MAGP2 Chinese Name 纤微丝相关glycoprotein2抗体 Alias MAGP 2; MAGP2; MAGP-2; MFAP 5; MFAP5; MFAP-5; Microfibril associated glycoprotein 2; microfibrillar associated protein 5; Microfibrillar associated protein 5 precursor; MP25.MFAP5_HUMAN Research Area Tumour immunology glycoprotein vascular endothelial cell Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 17kDa Cellular localization Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MAGP2: 101-173/173 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail MAGP2 (also known as Microfibril-associated glycoprotein 2, MFAP2, MP25 and Microfibrillar-associated protein 5 precursor) is a secreted, extracellular matrix protein which is a component of the elastin-associated microfibrils. It forms intermolecular disulfide bonds either with other MAGP2 molecules or with other components of the microfibrils. MAGP2 is upregulated in some ovarian cancers and is associated with poor survival of ovarian cancer patients.
Function:
Component of the elastin-associated microfibrils.
Subcellular Location:
Secreted, extracellular space, extracellular matrix.
Post-translational modifications:
Forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils.
N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycan heterogeneity at Thr-54: HexHexNAc (major) and HexHexNAc + sulfate (minor).
Similarity:
Belongs to the MFAP family.
SWISS:
Q13361
Gene ID:
8076
Database links:Entrez Gene: 8076 Human
Omim: 601103 Human
SwissProt: Q13361 Human
Unigene: 512842 Human
Scan Wechat Qrcode
Scan Whatsapp Qrcode