Product Name	PLAA
Chinese Name	磷脂酶A2激活蛋白抗体
Alias	PLAP_HUMAN; Phospholipase A-2-activating protein; PLAP; PLA2P; phospholipase A2 activating protein; DOA1; NDMSBA;
literatures	Specific References  (1)     |     SL3807R has been referenced in 1 publications. [IF=3.71] Rosing, Katharina, et al. Everolimus therapy is associated with reduced lipoprotein-associated phospholipase A2 (Lp-Pla2) activity and oxidative stress in heart transplant recipients. Atherosclerosis. 2013 Sep;230(1):164-70.  WB ;  Human, Mouse.   PubMed:23958269
Research Area	Cell biology  immunology  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	87kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Phospholipase A2 activator protein: 101-200/795
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha. SWISS: Q9Y263 Gene ID: 9373 Database links: Entrez Gene: 9373 Human Omim: 603873 Human SwissProt: Q9Y263 Human Unigene: 27182 Human 磷脂酶A2激活蛋白能激活磷脂酶A2，是类花生酸形成的一个重要中介体。作为促炎症反应剂，PLAP存在于类风湿性关节炎患者的炎症组织和滑膜液，因而被认为在炎症性疾病调控中发挥重要作用。IL-1β和TNF-α能刺激PLAP的形成。PLAP作为睾丸精原细胞瘤的Maker。

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