Product Name	Mammaglobin B
Chinese Name	乳腺珠蛋白2抗体
Alias	Lipophilin C; LPHC; Mammaglobin 2; MGB2; MGC71973; SCGB2A1; Secretoglobin, family 2A, member 1; UGB3.
Research Area	Tumour  immunology  Binding protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Rat, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	8.5kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Mammaglobin B: 41-95/95
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Mammaglobin B may bind androgens and other steroids, it may also bind estramustine, a chemotherapeutic agent used for prostate cancer. It may be under transcriptional regulation of steroid hormones. Subunit: Heterodimer of a lipophilin A and a lipophilin C (mammaglobin B) monomer associated head to head. Tissue Specificity: Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. SWISS: O75556 Gene ID: 4246 乳腺球蛋白是一个乳腺相关glycoprotein，它是一个分泌素家族（包括子宫球蛋白和lipophilin）成员的远亲。与其他分泌素家族成员不同，乳腺球蛋白的mRNA在乳腺组织中特异表达。在石蜡组织切片的检测中，该抗体检测乳腺癌组织中的乳腺珠蛋白敏感度高达80%。当和其他乳腺特异标记如GCDFP-15联合应用时，检测乳腺珠蛋白敏感度高达84%。有资料表明检测乳腺球蛋白，在鉴定原发癌是否发生转移中起到至关重要的作用。

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