Product Name	Lambda Light Chain
Chinese Name	λ轻链抗体
Alias	Ig lambda chain C regions; Bence Jones protein; BJP; Constant region of lambda light chains; IGLC 1; IGLC 2; IGLC 3; IGLC; IGLC1; IGLC2; IGLC3; LAC1_HUMAN; Immunoglobulin lambda constant 1; Mcg marker; Paraprotein; Ig lambda-1 chain C regions.
literatures	Specific References  (1)     |     SL3801R has been referenced in 1 publications. [IF=5.241] Dou, Aixia. et al. Reelin depletion alleviates multiple myeloma bone disease by promoting osteogenesis and inhibiting osteolysis. Cell Death Discov. 2021 Aug;7(1):1-10  IHC ;  Mouse.   PubMed:34433809
Research Area	Tumour  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	22.5kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Lambda Light Chain: 41-106/106
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. Subcellular Location: Cytoplasmic Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. SWISS: P01701 Gene ID: 3535 Database links: Entrez Gene: 3535 Human Entrez Gene: 3546 Human Entrez Gene: 8217 Human Omim: 147220 Human SwissProt: P01701 Human SwissProt: P01842 Human 该抗体特异识别免疫球蛋白λ轻链，可用于鉴定白血病、浆细胞瘤以及某些非霍奇金氏淋巴瘤。这些Tumour的共同特征是只限于单个轻链的表达，因此轻链Kappa和Lamda可用于良恶性淋巴病变（反应性lymphocyte增生和淋巴瘤）的辅助性诊断。

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