Product Name	NADPH oxidase 3
Chinese Name	NADPH oxidase 3抗体
Alias	Mitogenic oxidase 2; MOX 2; MOX2; NADPH oxidase 3; NADPH oxidase catalytic subunit-like 3; NOX 3; NOX3; GP91 3; GP91-3; gp91phox homolog 3.
literatures	Specific References  (4)     |     SL3683R has been referenced in 4 publications. [IF=9.83] Wakatsuki, Shuji, et al. "Oxidative stress–dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." The Journal of cell biology(2015): jcb-201506102.  IHC-P ;  Mouse.   PubMed:26572622 [IF=5.33] Shuji Wakatsuki. et al. Selective phosphorylation of serine 345 on p47-phox serves as a priming signal of ROS-mediated axonal degeneration. Exp Neurol. 2022 Jun;352:114024  WB ;  Mouse.   PubMed:10.1016/j.expneurol.2022.114024 [IF=4.011] Kim YR et al. Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis. Sci Rep. 2020 Mar 12;10(1):4570.  IP ;  mouse.   PubMed:32165681 [IF=3.448] Ma Q et al. Non‐coenzyme role of vitamin B1 in RANKL‐induced osteoclastogenesis and ovariectomy induced osteoporosis. J Cell Biochem. 2020 Feb 26.  WB ;  mouse.   PubMed:32100911
Research Area	Cell biology  immunology  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	65kDa
Cellular localization	cytoplasmic The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Nox3/NADPH oxidase 3: 65-160/568
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. SWISS: Q9HBY0 Gene ID: 50508 Database links: Entrez Gene: 50508 Human Entrez Gene: 224480 Mouse Entrez Gene: 292279 Rat Omim: 607105 Human SwissProt: Q9HBY0 Human SwissProt: Q672J9 Mouse SwissProt: Q672K1 Rat Unigene: 247776 Human Unigene: 328756 Mouse Unigene: 161761 Rat

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