Product Name	KIF17
Chinese Name	驱动蛋白家族KIF17抗体
Alias	KIAA1405; KIF 17; KIF 17B; KIF 3X; KIF17B; KIF3-related motor protein; KIF3X; Kinesin family member 17; Kinesin like protein KIF 17; Kinesin like protein KIF17; KIF17_HUMAN.
Research Area	Tumour  immunology  Neurobiology  Signal transduction  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	115kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human KIF17: 201-300/1029
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The kinesin superfamily of proteins (KIFs) consists of a class of microtubule-dependent motors that play a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The kinesin proteins are involved in organelle transport and are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria. They also mediate transport between the endoplasmic reticulum (ER) and the Golgi complex. In neurons, kinesin motors conduct vesicular transport, such as of synaptic vesicle components to axons and of neurotransmitter receptors to dendrites. KIF17 belongs to the functionally diverse subgroup of the kinesin superfamily characterized by a N-terminal motor domain (N-IV class), that includes the KIF3 motor protein. KIF17 is specifically expressed in the brain, present in abundance in the gray matter, particularly in the hippocampus and cerebral cortex, but not in the white matter such as the optic nerve. Function: Transports vesicles containing N-methyl-D-aspartate(NMDA) receptor 2B along microtubules (By similarity). Subunit: Interacts with LIN-10 PDZ domain. Interacts with PIWIL1(By similarity). Interacts with TBATA (By similarity). Subcellular Location: Cytoplasm, cytoskeleton (Probable). Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. SWISS: Q9P2E2 Gene ID: 57576 Database links: Entrez Gene: 57576 Human Entrez Gene: 16559 Mouse Omim: 605037 Human SwissProt: Q9P2E2 Human SwissProt: Q99PW8 Mouse Unigene: 130411 Human Unigene: 271936 Mouse
Product Picture	Sample: HepG2 Cell Lysate at 30 ug Primary: Anti-KIF17 (SL3527R) at 1:300 dilution; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bse-0295G-HRP) at 1: 5000 dilution; Predicted band size :115 kD Observed band size :115 kD

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