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Product Name SIGLEC14 Chinese Name 唾液酸结合性免疫球蛋白样凝集素14抗体 Alias Sialic acid binding Ig like lectin 14; Siglec 14; Siglec-14; SIG14_HUMAN. Research Area Tumour Cell biology immunology transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 42kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SIGLEC14: 51-150/396 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail SIGLEC14 is a putative adhesion molecule. It may activate associated receptors.
Function:
Putative adhesion molecule. Sialic acid-binding pairedreceptor which may activate associated receptors.
Subunit:
Interacts with TYROBP.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity:
Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver. Also detected in lung and testis.
Similarity:
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
SWISS:
Q08ET2
Gene ID:
100049587
Database links:Entrez Gene: 100049587 Human
SwissProt: Q08ET2 Human
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