Product Name	LDHA
Chinese Name	乳酸脱氢酶抗体
Alias	Lactate Dehydrogenase; Lactate Dehydrogenase Isoenzyme V; Lactate Dehydrogenase isozyme H4; L lactate dehydrogenase A chain; Lactate dehydrogenase A; Lactate dehydrogenase A chain; LDH A; LDH heart subunit; LDH M; LDHM; LDH muscle subunit; LDH1; LDHA; PIG 19; PIG19; Proliferation inducing gene 19 protein; TRG 5; TRG5; LDHA_HUMAN.
Research Area	Tumour  Cell biology  Signal transduction  Kinases and Phosphatases  TumourCell biologyMaker
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,
Applications	WB=1:500-2000 IHC-P=1:100-500 IF=1:10-50 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	37kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LDHA
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq]. Subunit: Homotetramer. Subcellular Location: Cytoplasm. Post-translational modifications: ISGylated. DISEASE: Glycogen storage disease 11 (GSD11) [MIM:612933]: A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the LDH/MDH superfamily. LDH family. SWISS: P00338 Gene ID: 3939 Database links: Entrez Gene: 3939 Human Entrez Gene: 16828 Mouse Entrez Gene: 24533 Rat Omim: 150000 Human SwissProt: P00338 Human SwissProt: P06151 Mouse SwissProt: P04642 Rat Unigene: 2795 Human Unigene: 29324 Mouse Unigene: 107896 Rat
Product Picture	Sample: Lane 1: Muscle (Mouse) Tissue Lysate at 40 ug Lane 2: Liver (Mouse) TissueLysate at 40 ug Lane 3: Kidney (Mouse) Tissue Lysate at 40 ug Lane 4: Small intestine (Mouse) Tissue Lysate at 40 ug Lane 5: Muscle (Rat) Tissue Lysate at 40 ug Lane 6: Liver (Rat) Tissue Lysate at 40 ug Lane 7: Hela (Human) Cell Lysate at 30 ug Lane 8: 293T (Human) Cell Lysate at 30 ug Lane 9: MCF-7 (Human) Cell Lysate at 30 ug Lane 10: Molt-4 (Human) Cell Lysate at 30 ug Primary: Anti-LDHA (SL34202R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 37 kD Observed band size: 35 kD

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