Product Name	SLC15A1
Chinese Name	肠道肽Transporter1/小肽Transporter1抗体
Alias	SLC15A1; Oligopeptide transporter, small intestine isoform; Peptide transporter 1; Intestinal H(+)/peptide cotransporter; Solute carrier family 15 member 1(SLC15A1); +peptide cotransporter; HPECT1; HPEPT1; Human peptide transporter (HPEPT1) mRNA complete cds; Intestinal H; Oligopeptide transporter small intestine isoform; PEPT1; Peptide transporter 1; Solute carrier family 15 (oligopeptide transporter) member 1; S15A1_HUMAN.
literatures	Specific References  (1)     |     SL34065R has been referenced in 1 publications. [IF=8.947] Liping Sun. et al. Rational design of mixed nanomicelle eye drops with structural integrity investigation. Acta Biomater. 2022 Jan;:  IF ;  Human.   PubMed:35032720
Research Area	Signal transduction  Channel protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,
Applications	WB=1:500-1000 IHC-P=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	79kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC15A1
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	PEPT1(Oligopeptide transporter, small intestine isoform (Peptide transporter 1) (Intestinal H(+)/peptide cotransporter) (Solute carrier family 15 member 1) Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. Subcellular Location：membrane; Multi-pass membrane protein. Tissue Specificity Intestine, kidney, liver and low in brain. Belongs to the PTR2/POT transporter (TC 2.A.17) family. Function: Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. SWISS: Q90WH8 Gene ID: 6564 Database links: Entrez Gene: 6564 Human Omim: 600544 Human SwissProt: P46059 Human Unigene: 436893 Human 小肽Transporter又称寡肽Transporter; 小肽是蛋白质在动物体内消化的主要产物，而位于小肠刷状缘膜上的小肽Transporter 在小肽的吸收过程中发挥重要作用，因此PepT1的活性直接影响小肽的吸收。 PepT1主要在消化道中表达，在肾脏中也有微弱的表达。PepT1是低親和力、高容量的肽載體PepT2是高親和力、低容量的肽載體。PepT2主要在腎臟中表達。
Product Picture	Sample: Lane 1: Liver (Mouse) Lysate at 40 ug Lane 2: Liver (Rat) Lysate at 40 ug Lane 3: Panc-1 (Human) Cell Lysate at 30 ug Primary: Anti-SLC15A1 (SL34065R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 80 kD Observed band size: 83 kD Paraformaldehyde-fixed, paraffin embedded (human gastric carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC15A1) Polyclonal Antibody, Unconjugated (SL34065R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC15A1) Polyclonal Antibody, Unconjugated (SL34065R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (rat small intestine); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC15A1) Polyclonal Antibody, Unconjugated (SL34065R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (Mouse small intestine); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC15A1) Polyclonal Antibody, Unconjugated (SL34065R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC15A1) Polyclonal Antibody, Unconjugated (SL34065R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (mouse kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC15A1) Polyclonal Antibody, Unconjugated (SL34065R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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