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Mouse Anti-TSHB antibody
Mouse Anti-TSHB antibody
TSHB_HUMAN; Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta (TSH-B; TSH-beta); Thyrotropin beta chain; Thyrotropin alfa; TSH-β;
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  • NO.:SL2676M
    Clonality:Polyclonal
    Immunogen Species:Mouse
    React Species:(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,)
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name TSHB
Chinese Name 促甲状腺素β亚单位抗体
Alias TSHB_HUMAN; Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta (TSH-B; TSH-beta); Thyrotropin beta chain; Thyrotropin alfa; TSH-β;   
Research Area immunology  Growth factors and hormones  Endocrinopathy  
Immunogen Species Mouse
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 15kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human TSHB: 51-138/138 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Function:
Indispensable for the control of thyroid structure and metabolism.

Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

Subcellular Location:
Secreted.

Similarity:
Belongs to the glycoprotein hormones subunit beta family.

SWISS:
P01222

Gene ID:
7252

Database links:

Entrez Gene: 7252 Human

Entrez Gene: 100302414 Rabbit

SwissProt: P01222 Human



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