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Product Name LIR-6/LILRA1 Chinese Name 白细胞免疫球蛋白样受体6抗体 Alias CD85 antigen-like family member I; CD85i; Leukocyte immunoglobulin-like receptor 6; Leukocyte immunoglobulin-like receptor subfamily A member 1; Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1; Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 soluble isoform; LILRA1; LIR-6; LIR6; LIRA1_HUMAN. Research Area Cell biology immunology The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 52kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LIR6: 401-489/489 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Function:
May act as receptor for class I MHC antigens.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Detected in monocytes and B-cells.
Similarity:
Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
SWISS:
O75019
Gene ID:
11024
Database links:Entrez Gene: 11024 Human
Omim: 604810 Human
SwissProt: O75019 Human
Unigene: 710507 Human
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