Product Name	IL28A
Chinese Name	白细胞介素28A抗体
Alias	Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; EG330496; Ifnl2; IFNL2_HUMAN.
literatures	Specific References  (1)     |     SL2627R has been referenced in 1 publications. [IF=0] Wang et al. Altered Expression of IFN-λ2 in Allergic Airway Disorders and Identification of Its Cell Origins. (2016) Mediators.Inflam. 2016:5759496  FCM,IF(ICC) ;  Human.   PubMed:27057098
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Dog, Pig, Cow, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	20kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IL-28A: 131-200/200
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008] Function: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Subcellular Location: Secreted. Similarity: Belongs to the lambda interferon family. SWISS: Q8IZJ0 Gene ID: 282616 Database links: Entrez Gene: 282616 Human Entrez Gene: 330496 Mouse Omim: 607401 Human SwissProt: Q8IZJ0 Human SwissProt: Q4VK74 Mouse Unigene: 567792 Human Unigene: 454510 Mouse

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