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Product Name IL17RC Chinese Name 白介素17受体C抗体 Alias IL-17RL; Interleukin-17 receptor C; IL 17 receptor C; IL 17RC; IL-17RC; IL 17RL; IL17 receptor C; IL17F receptor; IL17RL; Interleukin 17 receptor C; Interleukin 17 receptor homolog; Interleukin 17 receptor like; Interleukin 17 receptor like protein; I17RC_HUMAN. Research Area immunology The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Pig, Cow, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 85kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IL-17RC: 151-250/791 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail IL17RC is a single pass transmembrane protein that shares limited similarity with the interleukin 17 receptor. It is widely expressed in non leukocyte tissues and forms a heteromeric receptor for IL17 with IL17RA. At least four different isoforms are known to exist.
Function:
Cell membrane; Single-pass type I membrane protein. Note=Soluble isoforms may be produced.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate. Low expression in thymus and leukocytes. Expressed (at protein level) in prostate and prostate cancer, skeletal muscle, kidney and placenta.
SWISS:
Q8NAC3
Gene ID:
84818
Database links:Entrez Gene: 84818 Human
Omim: 610925 Human
SwissProt: Q8NAC3 Human
Product Picture Tissue/cell: human colon carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-IL-17RC/IL-17RL Polyclonal Antibody, Unconjugated(SL2607R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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