Product Name	Ly-6G
Chinese Name	lymphocyte抗原6G抗体
Alias	Gr-1; Gr1; Ly 6G; Ly-6G.1; Ly6G; lymphocyte antigen 6 complex locus G; Lymphocyte antigen 6G.
literatures	Specific References  (7)     |     SL2576R has been referenced in 7 publications. [IF=16.264] Schukur, Lina, et al. "Implantable synthetic cytokine converter cells with AND-gate logic treat experimental psoriasis." Science Translational Medicine7.318 (2015): 318ra201-318ra201.  IHC-P ;  Mouse.   PubMed:26676608 [IF=6.17] Ying Xu. et al. PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation. Free Radical Bio Med. 2020 Nov;160:871  IF,IHC ;  Mouse.   PubMed:32947010 [IF=4.12] Arecco et al. Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation. (2016) Sci.Rep. 6:24708  IF ;  Mouse.   PubMed:27241590 [IF=2.319] Xinhong WANG. et al. Anti-inflammatory effect of HGF responses to oral traumatic ulcers using an HGF-Tg mouse model. 2021 Nov 25  IHC ;  Mouse.   PubMed:34819402 [IF=0] Stephanie Arnold. et al. Single and Multiplex Immunohistochemistry to Detect Platelets and Neutrophils in Rat and Porcine Tissues. Methods and Protocols. 2022 Oct;5(5):71  IHC ;  Rat, Pig.   PubMed:36136817 [IF=0] Wanga X et al. Anti-inflammatory effect of HGF responses to traumatic oral ulcers using an HGF-Tg mouse model. Research Square; 2020 Jan 22.  IHC-P ;  Mouse.   PubMed:doi:10.21203/rs.2.21478/v1 [IF=0] Tsunashima et al. Accumulated myeloid-derived suppressor cells demonstrate distinct phenotypes and functions in two non-alcoholic steatohepatitis mouse models. (2015) Hepatobiliary.Surg.Nutr. 4:313-319  FC/FACS,IHC ;  Mouse.   PubMed:26605278
Research Area	Cell biology  immunology  Stem cells  Cell Surface Molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	14kDa
Detection molecular weight	21-25 kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse Ly-6G/Gr-1: 51-134/134
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor (By similarity). Tissue Specificity: Expressed in bone marrow. Similarity: Contains 1 UPAR/Ly6 domain. SWISS: P35461 Gene ID: 546644 Database links: Entrez Gene: 546644 Mouse SwissProt: P35461 Mouse Ly6G属于是Ly-6家族成员,主要表达于T细胞、单核细胞，中性白细胞等，在抑制抗Tumour和T细胞的应答方面起着重要作用。主要定位于The cell membrane、cytoplasmic。
Product Picture	Lane 1: Recombinant mouse Ly-6G protein (His-tag) Primary: Anti-Ly-6G (SL2576R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 18 kDa s

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