Product Name	Glycophorin A
Chinese Name	血型glycoproteinA（CD235a）抗体
Alias	AI853584; CD235a; GPA; GYPA; Blood group--MN locus; CD235a antigen; Glycophorin A (MNS blood group); Glycophorin A includes MN blood group; Glycophorin A precursor; Glycophorin A, included; GlycophorinA; GPA; GPErik; GpMiIII; GPSAT; GYPA; GYPA, included; HGpMiIII; HgpMiV; HgpMiX; HgpMiXI; HGpSta(C); MN; MN sialoglycoprotein; MNS; PAS 2; PAS-2; PAS2;Sialoglycoprotein alpha; GLPA_MOUSE.
literatures	Specific References  (1)     |     SL2575R has been referenced in 1 publications. [IF=6.8] Khan, Mohammad Badruzzaman. et al. Exercise Improves Cerebral Blood Flow and Functional Outcomes in an Experimental Mouse Model of Vascular Cognitive Impairment and Dementia (VCID). TRANSL STROKE RES. 2023 Jan;:1-16  FCM ;  Mouse.   PubMed:36689081
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	14kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse GPA: 74-150/150
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008] Function: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). Subunit: Homodimer. Interacts with Streptococcus gordonii has protein. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Note=Appears to be colocalized with SLC4A1. Similarity: Belongs to the glycophorin A family. SWISS: P14220 Gene ID: 14934 Database links: Entrez Gene: 2993 Human Entrez Gene: 14934 Mouse Omim: 111300 Human SwissProt: P02724 Human SwissProt: P14220 Mouse Unigene: 434973 Human Unigene: 13123 Mouse
Product Picture	Sample: Lane 1: Blood cell (Mouse) Lysate at 40 ug Lane 2: Lung (Mouse) Lysate at 40 ug Lane 3: Kidney (Mouse) Lysate at 40 ug Lane 4: Placenta (Mouse) Lysate at 40 ug Lane 5: Spleen (Mouse) Lysate at 40 ug Primary: Anti-Glycophorin A (SL2575R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD Sample: Lane 1: K562 (Human) Cell Lysate at 30 ug Lane 2: HL60 (Human) Cell Lysate at 30 ug Lane 3: Molt-4 (Human) Cell Lysate at 30 ug Lane 4: Jurkat (Human) Cell Lysate at 30 ug Lane 5: 293T (Human) Cell Lysate at 30 ug Primary: Anti-Glycophorin A (SL2575R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD Western blot analysis of extracts from bone using Glycophorin antibody. (Primary dilution:1:300)

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