Product Name	COX7A2
Chinese Name	细胞色素c氧化酶7A2抗体
Alias	Mitochondrion. Cytochrome c oxidase subunit 7A2, mitochondrial; COX7a related protein; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-liver/heart; COX7a-related protein; COX7AR; COX7RP; Cytochrome c oxidase subunit VIIa related protein, mitochondrial; Cytochrome c oxidase subunit VIIaL; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-related protein, mitochondrial [Precursor]; EB1; Estrogen receptor binding CpG island; SIG81; CX7A2_HUMAN.
Research Area	Tumour  Cardiovascular  Signal transduction  Synthesis and Degradation  Mitochondrion
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	6.7 kDa
Cellular localization	cytoplasmic The cell membrane Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human COX7A2: 21-83/83
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009] Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Subcellular Location: Mitochondrion inner membrane. Similarity: Belongs to the cytochrome c oxidase VIIa family. SWISS: P14406 Gene ID: 1347 Database links: Entrez Gene: 1347 Human Entrez Gene: 12866 Mouse Entrez Gene: 29507 Rat Omim: 123996 Human SwissProt: P14406 Human SwissProt: P48771 Mouse SwissProt: P35171 Rat Unigene: 70312 Human Unigene: 152627 Mouse Unigene: 1745 Rat

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