Product Name	GRO gamma
Chinese Name	生长调节致癌基因gamma/GRＯγ抗体
Alias	growthregulated oncogene gamma; Chemokine (CXC motif) ligand 3; Cinc 2; Cinc2; CINC2b; CXCL 3; CXCL3; Cytokine induced neutrophil chemoattractant 2; Dcip1; Dendritic cell inflammatory protein 1; Gm1960; GRO3; GRO3 oncogene; GROG; Growth regulated protein gamma; Macrophage inflammatory protein 2 beta precursor; Melanoma growth stimulatory activity gamma; MGSA gamma; MIP 2b; MIP2B; SCYB3; CXCL3_HUMAN.  GRＯγ; GRＯ-γ; GRＯ γ.
literatures	Specific References  (4)     |     SL2547R has been referenced in 4 publications. [IF=6.166] Sugandha Saxena. et al. Differential expression profile of CXC-receptor-2 ligands as potential biomarkers in pancreatic ductal adenocarcinoma. Am J Cancer Res. 2022; 12(1): 68–90  IHC ;  Mouse,Human.   PubMed:35141005 [IF=3.762] Wu L et al. Interleukin17–CXCR2 axis facilitates breast cancer progression by up-regulating neutrophil recruitment. Am J Pathol. 2019 Oct 22. pii: S0002-9440(19)30768-0.  IHC-P ;  Mouse.   PubMed:31654638 [IF=3.53] Gui S, Ni S, Jia J, Gong Y, Gao L, et al. (2014) Inconformity of CXCL3 Plasma Level and Placenta Expression in Preeclampsia and Its Effect on Trophoblast Viability and Invasion. PLoS ONE 9(12): e114408.  IHC-P ;  Human.   PubMed:25485631 [IF=2.766] Gui et al. Inconformity of CXCL3 plasma level and placenta expression in preeclampsia and its effect on trophoblast viability and invasion. (2014) PLoS.One. 9:e114408  IHC ;  Human.   PubMed:25485631
Research Area	Tumour  immunology  Growth factors and hormones
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	12kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GRO gamma: 35-107/107
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Growth Regulated Protein gamma (GRO gamma) is a cytokine that may play a role in inflammation and affects endothelial cells in an autocrine fashion. It belongs to the intercrine alpha family (small cytokine c-x-c) (chemokine cxc). Function: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Subcellular Location: Secreted. Post-translational modifications: N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. Similarity: Belongs to the intercrine alpha (chemokine CxC) family. SWISS: P19876 Gene ID: 2921 Database links: Entrez Gene: 2921 Human Omim: 139111 Human SwissProt: P19876 Human Unigene: 89690 Human 黑素瘤生长刺激因子3.

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