Product Name	CD83
Chinese Name	CD83抗体
Alias	B cell activation 45kDa cell surface glycoprotein Ig superfamily; B cell activation protein; BL11; BL11 PEN; CD83 molecule; Cell surface protein HB15; HB15; MGC130312; MGC130313; Cell surface protein HB15; CD83_HUMAN.
literatures	Specific References  (2)     |     SL2519R has been referenced in 2 publications. [IF=3.272] Miss Hongfang Meng. et al. Overexpression of hepatocyte growth factor in dental pulp stem cells ameliorates the severity of psoriasis by reducing inflammatory responses. 2021 Jun 22  IHC ;  Mouse.   PubMed:34155928 [IF=1.48] Zhang, Suxin, et al. "Variation and significance of secretory immunoglobulin A, interleukin 6 and dendritic cells in oral cancer." Oncology Letters.  IHC-P ;  Human.   PubMed:28454394
Research Area	immunology  The cell membrane受体  t-lymphocyte  b-lymphocyte
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	21kDa
Detection molecular weight	43 kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CD83: 121-196/196 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Function: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation (By similarity). Subunit: Monomer. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Abundantly expressed in spleen and brain, but is also detected in most tissues analyzed. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: Q01151 Gene ID: 9308 Database links: Entrez Gene: 9308 Human Entrez Gene: 12522 Mouse Entrez Gene: 361226 Rat Omim: 604534 Human SwissProt: Q01151 Human SwissProt: O88324 Mouse Unigene: 595133 Human Unigene: 57175 Mouse Unigene: 20096 Rat
Product Picture	Sample: Lane 1: Mouse Bone tissue lysates Lane 2: Rat Bone tissue lysates Primary: Anti-CD83 (SL2519R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 21 kDa Observed band size: 44 kDa

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