Product Name	KIF5B
Chinese Name	驱动蛋白KNS1抗体
Alias	Conventional kinesin heavy chain; KIF5B; Kinesin 1 (110-120kD); Kinesin family member 5B; Kinesin heavy chain; Kinesin heavy chain ubiquitous; Kinesin-1 heavy chain; KINH; KINH_HUMAN; KNS 1; KNS; KNS1; Ubiquitous kinesin heavy chain; UKHC.
Research Area	Neurobiology  Signal transduction  Cell adhesion molecule  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	106kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human KIF5B: 1-100/963
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Structural proteins in Arabidopsis provide cellular stability, facilitate protein transportation within the cell and are essential for cell growth. Three types of molecular motors are involved in the organization, dynamics and transport processes associated with the cytoskeleton (1). They include myosin, which transports cargo along actin filaments, and kinesin and dynein, which transport cargo along microtubules (1,2). These proteins regulate many cellular functions, including cell division and expansion, cell-to-cell communication, membrane trafficking and morphogenesis (2). In addition, the dynamin-like proteins are GTP-binding proteins involved in vesicle trafficking (3). Extensin is a structural protein that may be involved in cell wall assembly, while expansin is a cell wall loosening protein that induces stress relaxation and extension of cell walls and may control organ size, morphology and abscission (4,5). Also, xyloglucan (XG), a major hemicellulose in plants, is modified by the fucosyltransferase, XG FTase, which adds a terminal fucosyl residue to XG (6). Function: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Subunit: Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 and PPP1R42 (By similarity). Interacts with SYBU. Interacts with JAKMIP1. Interacts with PLEKHM2. Interacts with ECM29. Subcellular Location: Cytoplasm, cytoskeleton. Note=Uniformly distributed between soma and neurites in hippocampal neurons. Similarity: Belongs to the kinesin-like protein family. Kinesin subfamily. Contains 1 kinesin-motor domain. SWISS: P33176 Gene ID: 3799 Database links: Entrez Gene: 3799 Human Entrez Gene: 16573 Mouse Entrez Gene: 117550 Rat Omim: 602809 Human SwissProt: P33176 Human SwissProt: Q61768 Mouse SwissProt: Q2PQA9 Rat Unigene: 327736 Human Unigene: 644646 Human Unigene: 223744 Mouse Unigene: 4046 Rat
Product Picture	Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Testis tissue lysates Lane 3: Rat Cerebrum tissue lysates Lane 4: Human MCF-7 cell lysates Lane 5: Human HepG2 cell lysates Primary: Anti-Kinesin/KIF5B (SL24716R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 106 kD Observed band size: 110 kD

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