Product Name	CCL3
Chinese Name	巨噬细胞炎性蛋白1α抗体
Alias	Tonsillar lymphocyte LD78 alpha protein; CCL 3; CCL3; Chemokine C C motif ligand 3; Chemokine CC Motif Ligand 3; G0/G1 switch regulatory protein 19 1; G0S19 1; G0S19 1 protein; Heparin binding chemotaxis protein antibody L2G25B; LD78ALPHA; Macrophage inflammatory protein 1 alpha; MIP 1 alpha; MIP-1 Alpha; MIP 1A; MIP1A; PAT 464.1; SCYA 3; SCYA3; SIS alpha; SIS beta; Small inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; CCL3_HUMAN; CCL3_MOUSE;   MIP-1α; MIP-1-α; MIP 1 α; MIP1α; MIP1-α.
literatures	Specific References  (2)     |     SL2452R has been referenced in 2 publications. [IF=3.454] Odum James D.. et al. Candidate Biomarkers for Sepsis-Associated Acute Kidney Injury Mechanistic Studies. SHOCK. 2022 May;57(5):687-693  IHC ;  Mouse.   PubMed:35234208 [IF=3.298] Qiu et al. Therapeutic Potential of Pien Tze Huang on Experimental Autoimmune Encephalomyelitis Rat. (2018) J.Immunol.Res. 2018:2952471  IHC ;  Rat.   PubMed:29682587
Research Area	Tumour  immunology  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	7.9kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse CCL3: 24-92/92
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010] Function: Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils. Subcellular Location: Secreted. Tissue Specificity: Expressed in lung, spleen, and pancreas. Similarity: Belongs to the intercrine beta (chemokine CC) family. SWISS: P10855 Gene ID: 20302 Database links: Entrez Gene: 6348 Human Entrez Gene: 20302 Mouse Entrez Gene: 25542 Rat Omim: 182283 Human SwissProt: P10147 Human SwissProt: P10855 Mouse SwissProt: P50229 Rat Unigene: 514107 Human Unigene: 1282 Mouse Unigene: 10139 Rat

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