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Product Name FPR1 Chinese Name 甲酸基肽受体1抗体 Alias Formyl peptide receptor 1; fMet Leu Phe receptor; FMLP; FMLP Receptor; FPR 1; FPR; N formyl peptide chemoattractant receptor; N formyl peptide receptor; N formylpeptide chemoattractant receptor; fMet-Leu-Phe receptor; FMLPR; FPR; FPR receptor; FPR1; FPR1_MOUSE; N formylpeptide chemoattractant receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor. Research Area Signal transduction transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 40kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse FPR1: 131-230/364 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]
Function:
High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Similarity:
Cell membrane; Multi-pass membrane protein.
SWISS:
P33766
Gene ID:
14293
Database links:
UniProtKB - P33766
transcriptional regulatory factor(Transcriptin Regulators) FPR1属于G protein-coupled receptor家族成员,参与细胞信号传导,激活MAPK通路,免疫应答。Product Picture Sample:
Spleen (Mouse) Lysate at 40 ug
Primary: Anti-FPR1 (SL23519R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kD
Observed band size: 55 kD
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